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X-WR-CALDESC:Events for SFB 1551
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DTSTART:20240101T000000
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BEGIN:VEVENT
DTSTART;TZID=UTC:20251204T103000
DTEND;TZID=UTC:20251204T113000
DTSTAMP:20251203T124439Z
CREATED:20250313T135921Z
LAST-MODIFIED:20251203T124439Z
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SUMMARY:SFB 1551 Seminar Series Event - Prof. Dr. Pol Besenius
DESCRIPTION:Methods talk by Prof. Dr. Pol Besenius\, Chemistry Department\, Johannes Gutenberg University \nWeak Non-Covalent Interactions in Biopolymer and Synthetic Supramolecular Assemblies \nThis lecture introduces the basic principles that define modern supramolecular chemistry through a historical and conceptual overview of non-covalent interactions. We will examine the nomenclature and evolution of key interaction types\, including hydrogen bonding\, Coulomb interactions\, π–π stacking and related interactions in aromatic systems. Emphasis will be placed on understanding how enthalpic and entropic contributions govern the formation\, strength\, and selectivity of supramolecular assemblies. Finally\, we will explore the crucial role of the solvent environment—highlighting solvation and solvophobic effects in (macro)molecular recognition and self-assembly. These elements provide a framework for analyzing and designing non-covalent systems across chemistry\, biology\, and materials science.
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-prof-dr-pol-besenius/
LOCATION:Biocenter I\, EG 00.187\, Hanns-Dieter-Hüsch-Weg 15\, Mainz
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BEGIN:VEVENT
DTSTART;TZID=UTC:20251205T090000
DTEND;TZID=UTC:20251205T100000
DTSTAMP:20251124T095029Z
CREATED:20251124T095029Z
LAST-MODIFIED:20251124T095029Z
UID:10000107-1764925200-1764928800@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Dr. Sergio Cruz-Leon
DESCRIPTION:“Bridging cellular 3D imaging with physics-based simulations for biological discovery” \nDr. Sergio Cruz-Leon (MPI Biophysics\, Frankfurt) \nSummary: \nCellular function is governed by the structure\, location\, and dynamics of its densely packed molecular machines. Cryo-electron tomography (cryoET) captures 3D snapshots of intact cells at near molecular resolution. However\, extracting reliable molecular identities and interactions from tomographic data remains challenging. \nI will show how high-confidence 3D template matching (hcTM) for cryoET [1]\, coupled with multiscaling\, enables us to model and simulate biological landscapes directly from cryoET data [1-3]. hcTM reliably localizes a wide range of macromolecular complexes in crowded cytoplasm and nuclei\, producing spatial maps that are the basis to build simulation-ready models of subcellular environments. \nUsing this framework\, we uncovered vault particles loaded with ribosomal cargo [1] and the unexpected ‘cracking’ of the nuclear pore complex (NPC) during HIV passage [2]\, and resolved the molecular architecture of human chromatin in situ [3]. We then applied it to an autophagy-related condensate directly in cells\, demonstrating that a single amino-acid substitution strengthens intermolecular interactions\, drives a liquid-to-glass mesoscale transition\, and abolishes autophagic clearance. We thereby link a molecular alteration to changes in condensate material properties and biological function. \nIntegrating in situ imaging with multiscale simulation provides a pipeline for visual proteomics and sets the stage for simulating cellular processes in their native context. \n  \nKeywords: Visual proteomics\, cryoET\, high-confidence template matching\, multi-scale simulations\, HIV\, chromatin\, biomolecular condensates. \n  \n[1] Cruz-León\, et al.\, Nat. Comm.\, 2024 \n[2] Kreysing*\, Heidari*\, Zila*\, et al.\, Cell\, 2025 \n[3] Kreysing*\, Cruz-León*\, Betz*\, et al.\, BioRxiv\, 2025
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-dr-sergio-cruz-leon/
LOCATION:BZ2 Room 02.721 (2nd floor)\, Hans-Dieter-Hüsch-Weg 17\, Mainz\, Germany
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BEGIN:VEVENT
DTSTART;TZID=UTC:20251208T110000
DTEND;TZID=UTC:20251208T150000
DTSTAMP:20250903T150258Z
CREATED:20250714T085518Z
LAST-MODIFIED:20250903T150258Z
UID:10000104-1765191600-1765206000@crc1551.com
SUMMARY:SFB1551 IRTG Meeting - Pre-session for the Winter School
DESCRIPTION:More information soon! Stay tunned! \n 
URL:https://crc1551.com/our-event/sfb1551-irtg-meeting/
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BEGIN:VEVENT
DTSTART;TZID=UTC:20251211T160000
DTEND;TZID=UTC:20251211T170000
DTSTAMP:20251210T133407Z
CREATED:20251127T083527Z
LAST-MODIFIED:20251210T133407Z
UID:10000108-1765468800-1765472400@crc1551.com
SUMMARY:Joint Christmas Coloquium - Prof. Michael te Vrugt
DESCRIPTION:Dear all\, \nWe are excited to announce this year’s Joint Christmas Colloquium by the SFB 1551\, SFB 1552\, GenEvo\, 4R\, and SFB 1361.\nThe event will take place on Thursday\, 11 December starting from 16:00 at IMB’s Seminar Room followed by refreshments and networking. \nDue to unforeseen circumstances\, our originally invited speaker\, Prof. Gerald Haug\, is unable to attend and give his intended lecture. However\, we have found another great speaker\, Prof. Michael te Vrugt from the Institute of Physics at JGU\, who will share on “The Physics of a Zombie Apocalypse” \nMark your calendars for the event and come join us for the talk and merriment afterwards! \nDate: 11 December 2025\nTime: 16:00 – 17:00\, followed by get-together with refreshments\nVenue: IMB Seminar Room\, Ackermannweg 4\, 55128 Mainz \n 
URL:https://crc1551.com/our-event/joint-christmas-coloquium-prof-gerald-haug/
LOCATION:IMB Seminar Room\, Ackermannweg 4\, Mainz\, 55128\, Germany
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