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X-WR-CALDESC:Events for SFB 1551
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DTSTART;TZID=UTC:20240606T093000
DTEND;TZID=UTC:20240606T130000
DTSTAMP:20231201T131652Z
CREATED:20231201T131652Z
LAST-MODIFIED:20231201T131652Z
UID:10000056-1717666200-1717678800@crc1551.com
SUMMARY:Workshop with Prof. Heather Hofmeister (Joint Event with GenEvo\, 4R\, SFB1361\, and SFB1551)
DESCRIPTION:We are pleased to invite you to participate in a workshop with Prof. Heather Hofmeister entitled “Communication competencies in intercultural and intergenerational teams”. \nThis half-day workshop will focus on how to navigate conversations and differences in understanding each other based on different gender\, cultural backgrounds\, and expectations and locations in the power hierarchy and will be specifically designed for PhD students & early postdoctoral researchers from 4R\, GenEvo\, SFB 1361\, and SFB 1551. \nThe workshop will be held on Thursday\, June 6th\, from 9:30 to 13:00\, please mark your calendars!
URL:https://crc1551.com/our-event/workshop-with-prof-heather-hofmeister-joint-event-with-genevo-4r-sfb1361-and-sfb1551-talk-2/
LOCATION:IMB Seminar Room\, Ackermannweg 4\, Mainz\, 55128\, Germany
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20240514T080000
DTEND;TZID=UTC:20240517T170000
DTSTAMP:20231107T075614Z
CREATED:20230619T052240Z
LAST-MODIFIED:20231107T075614Z
UID:10000030-1715673600-1715965200@crc1551.com
SUMMARY:EMBO | EMBL Symposium: Cellular mechanisms driven by phase separation
DESCRIPTION:This conference will take place at EMBL Heidelberg\, with the option to attend virtually. \nRegistration is now open! Click the link below to register for on-site or virtual attendance! \nSymposium overview\nPhase separation is emerging as a common biophysical basis underlying many important cellular functions. This conference will bring together scientists from soft matter\, polymer physics\, molecular biology\, structural biology\, and cell and developmental biology to study condensates in biology and disease. Goals are \n\nto increase the awareness how important phase separation is for our understanding of many biological processes\nto explore the large repertoire of new tools generated by other disciplines that are ripe to be applied to complex problems related to phase separation\nto close the gap in transdisciplinary training to tackle the role of phase separation in biology\n\nFor more information please visit https://www.embl.org/about/info/course-and-conference-office/events/ees24-06/#vf-tabs__section-overview
URL:https://crc1551.com/our-event/embo-embl-symposium-cellular-mechanisms-driven-by-phase-separation/
LOCATION:EMBL\, Meyerhofstraße 1\, Heidelberg\, 69117
ATTACH;FMTTYPE=image/jpeg:https://crc1551.com/wp-content/uploads/2023/06/EES22-04_banner_3000x1000px-scaled-3.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20240502T103000
DTEND;TZID=UTC:20240502T113000
DTSTAMP:20240423T124150Z
CREATED:20230602T105656Z
LAST-MODIFIED:20240423T124150Z
UID:10000026-1714645800-1714649400@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Sina Wittmann
DESCRIPTION:Talk announcement for Sina Wittmann \nTitle: Protein condensation in the presence of nucleic acids \nIn the cell\, many protein condensates form by nucleic acid binding proteins. This is true in the cytoplasm as well as in the nucleus. An example of the former would be RNA-binding proteins forming stress granules and of the latter the nucleolus. However\, different physical phenomena can be behind these interactions. I will discuss different approaches of how to observe them experimentally.
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-sina-wittmann/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20240425T103000
DTEND;TZID=UTC:20240425T113000
DTSTAMP:20231211T090715Z
CREATED:20231211T090715Z
LAST-MODIFIED:20231211T090715Z
UID:10000058-1714041000-1714044600@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Prof. Dr. Tassula Proikas-Cezanne
DESCRIPTION:Talk announcement for Prof. Dr. Tassula Proikas-Cezanne. \n\nA role for WIPI beta propellers in autophagy and neurodegeneration \nBy Prof. Dr. Tassula Proikas-Cezanne \nEberhard Karls University Tübingen · Interfaculty Institute of Cell Biology (IFIZ)
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-prof-tassula-proikas-cezanne/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20240411T103000
DTEND;TZID=UTC:20240411T113000
DTSTAMP:20240319T135557Z
CREATED:20231102T133833Z
LAST-MODIFIED:20240319T135557Z
UID:10000045-1712831400-1712835000@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Prof. Dr. Jörg Höhfeld
DESCRIPTION:Talk announcement for Prof. Dr. Jörg Höhfeld. \n\nMaintaining the proteome under mechanical stress – from mechanisms to pathology \nBy Prof. Dr. Jörg Höhfeld \nUniversität Bonn · Institut für Zellbiologie \nAbstract from Prof. Höhfeld: \nOrganismal survival depends on the ability to maintain functional protein networks even under conditions that threaten protein integrity. Cells in multicellular organisms are constantly exposed to stress resulting from mechanical forces. In this situation\, protein homeostasis relies on a chaperone machinery that is organized by the co-chaperone BAG3. The BAG3-machinery recognizes force-unfolded cytoskeleton proteins and mediates their disposal through chaperone-assisted selective autophagy (CASA). In addition\, BAG3 interacts with components of the Hippo and mTOR signalling pathways to stimulate transcription and translation. This is important for compensating degradation during cytoskeleton maintenance. In agreement with its essential role under mechanical stress\, BAG3 deficiency causes severe muscle weakness in children and contributes to heart failure\, a leading cause of mortality in industrialized nations. Here\, we discuss the mode of action of the BAG3-machinery and its force-dependent regulation and pathophysiological relevance. 
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-prof-dr-joerg-hoefeld/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20240314T103000
DTEND;TZID=UTC:20240314T113000
DTSTAMP:20240228T144148Z
CREATED:20231115T091519Z
LAST-MODIFIED:20240228T144148Z
UID:10000047-1710412200-1710415800@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Prof. Dr. Ralf Metzler
DESCRIPTION:Talk announcement for Prof. Dr. Ralf Metzler. \n\n“Long-ranged correlated processes in disordered systems” \nBy Prof. Dr. Ralf Metzler \nUniversität Potsdam \nAbstract from Prof. Metzler: \nStochastic processes with long-ranged\, power-law correlations naturally emerge in systems such as Rouse polymers or single-file systems\, when all degrees of freedom are integrated out\, apart from the (tracer) particle of interest. In non-equilibrium situations\, the resulting overdamped dynamics corresponds to Mandelbrot’s fractional Brownian motion (FBM). \nThis talk will address some peculiar behaviours of FBM when subject to confinement in box potentials as well as sub- or superharmonic external potentials. Specifically\, it will be argued why superdiffusive FBM may be a good (polymer) model for growing serotonergic fibres in the mammalian brain. \nIn disordered environments it will be shown how non-Gaussian displacement density functions emerge and subtly depend on how the dynamics is introduced. This is achieved by stochastic-diffusivity models connected with long-range dependent noise. Moreover\, it will be discussed how time-dependent critical exponents can be introduced in this formalism. \nFinally\, amoeba systems will be introduced in which the displacement density function appears to converge to a non-Gaussian\, Laplace density.
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-prof-ralf-metzler/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20240304T090000
DTEND;TZID=UTC:20240307T170000
DTSTAMP:20231214T131637Z
CREATED:20230929T120846Z
LAST-MODIFIED:20231214T131637Z
UID:10000032-1709542800-1709830800@crc1551.com
SUMMARY:SFB1551 Winter School
DESCRIPTION:Content is protected.
URL:https://crc1551.com/our-event/sfb-1551-winter-school-2/
LOCATION:Kurpark-Hotel\, Schloßplatz 1-4\, Bad Dürkheim\, 67098\, Germany
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20240222T103000
DTEND;TZID=UTC:20240222T113000
DTSTAMP:20240118T094539Z
CREATED:20230602T105350Z
LAST-MODIFIED:20240118T094539Z
UID:10000023-1708597800-1708601400@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Prof. Dr. Konstanze Winklhofer
DESCRIPTION:Talk announcement for Prof. Dr. Konstanze Winklhofer \n\n“Linear polyubiquitin as a regulator of phase transitions in signaling and protein quality control” \nBy Prof. Dr. Konstanze Winklhofer \nRuhr-Universität Bochum
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-konstanze-winklhofer/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20240206T103000
DTEND;TZID=UTC:20240206T113000
DTSTAMP:20240118T091228Z
CREATED:20231120T140313Z
LAST-MODIFIED:20240118T091228Z
UID:10000048-1707215400-1707219000@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Prof. Dr. Andela Saric
DESCRIPTION:Talk announcement for Prof. Dr. Andela Saric. \n\n“Protein assemblies that split and merge cells across evolution” \nBy Prof. Dr. Andela Saric \nInstitute of Science and Technology Austria \nAbstract from Prof. Saric: \nI will present our recent research on the computational modelling of energy-consuming protein filaments that dynamically reshape and cut cells across evolution. I will first discuss the physical mechanism of ESCRT-III filaments that drive cell division and cell trafficking in archaea and eukaryotes. I will then discuss the physical mechanism behind the dynamic self-organisation of biochemically active FtsZ filaments in the early stages of bacterial division. Throughout\, I will present the comparisons of our models to in vitro and in vivo data. I will finish up with our recent thoughts on the shapes of symbiotic organisms that might have led to the emergence of eukaryotes.
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-prof-dr-andela-saric/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20240201T153000
DTEND;TZID=UTC:20240201T193000
DTSTAMP:20231128T155516Z
CREATED:20231128T155432Z
LAST-MODIFIED:20231128T155516Z
UID:10000053-1706801400-1706815800@crc1551.com
SUMMARY:Workshop with Prof. Heather Hofmeister (Joint Event with GenEvo\, 4R\, SFB1361\, and SFB1551)
DESCRIPTION:We are pleased to invite you to participate in a workshop with Prof. Heather Hofmeister entitled “Navigating challenging conversations within power hierarchies”. \nThis half-day workshop will focus on how to navigate “difficult” conversations and differences in understanding each other based on different gender\, cultural backgrounds\, and expectations and locations in the power hierarchy and will be specifically designed for PhD students & early postdoctoral researchers from 4R\, GenEvo\, SFB 1361\, and SFB 1551. \nThe workshop will be held on Thursday\, February 1st\, from 15:30 to 19:00\, followed by a pizza dinner. Please mark your calendars! Official registration for the workshop will follow in January. Participation will be credited with 2 hours (towards your IPP certificate). \nTo ensure that the workshop also addresses any more specific questions or requests\, please feel free to share them with us in advance using this link (anonymous).
URL:https://crc1551.com/our-event/workshop-with-prof-heather-hofmeister-joint-event-with-genevo-4r-sfb1361-and-sfb1551/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20240111T090000
DTEND;TZID=UTC:20240111T110000
DTSTAMP:20231129T122243Z
CREATED:20230602T105238Z
LAST-MODIFIED:20231129T122243Z
UID:10000022-1704963600-1704970800@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Dorothee Dormann
DESCRIPTION:Talk announcement for Dorothee Dormann. \n\nExperimental methods to study aggregation-prone RNA-binding proteins (part 2) \n 
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-dorothee-dormann-p2/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Amsterdam:20231214T110000
DTEND;TZID=Europe/Amsterdam:20231214T120000
DTSTAMP:20231122T132459Z
CREATED:20230918T134125Z
LAST-MODIFIED:20231122T132459Z
UID:10000041-1702551600-1702555200@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Prof. Dr. Christoph Weber
DESCRIPTION:Talk announcement for Prof. Dr. Christoph Weber.
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-christoph-weber/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20231213T160000
DTEND;TZID=UTC:20231213T160000
DTSTAMP:20231031T154437Z
CREATED:20231031T154226Z
LAST-MODIFIED:20231031T154437Z
UID:10000044-1702483200-1702483200@crc1551.com
SUMMARY:Christmas Colloquium (Jointly organised by SFB1361\, SFB1551\, GenEvo\, 4R-RTG)
DESCRIPTION:We are delighted to invite you all to a Christmas Colloquium on Wednesday\, 13 December 2023 starting at 16:00\, and followed by dinner and merriment! This is a joint event organised by SFB 1361\, SFB 1551\, GenEvo\, and 4R-RTG. \n  \nThere will be an interesting talk given by a 2023 Alexander von Humboldt Professorship recipient\, Prof. Hanna Kokko. She is a theoretical evolutionary biologist and is currently based in JGU carrying out research to better understand the interaction between evolutionary and ecological processes. \n  \nThe event is open to all members of the SFB 1361\, SFB 1551\, GenEvo\, and 4R-RTG. So\, mark your calendars and come join us in the IMB seminar room for the talk and get-together afterwards!
URL:https://crc1551.com/our-event/christmas-colloquium/
LOCATION:IMB Seminar Room\, Ackermannweg 4\, Mainz\, 55128\, Germany
ATTACH;FMTTYPE=image/jpeg:https://crc1551.com/wp-content/uploads/2023/10/1698766986013-fe51415e-d647-43fc-a112-6d5819b447da_1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20231207T103000
DTEND;TZID=UTC:20231207T113000
DTSTAMP:20231207T081958Z
CREATED:20230905T130135Z
LAST-MODIFIED:20231207T081958Z
UID:10000039-1701945000-1701948600@crc1551.com
SUMMARY:Postponed - SFB 1551 Seminar Series Event - Prof. Dr. Tassula Proikas-Cezanne
DESCRIPTION:Talk announcement for Prof. Dr. Tassula Proikas-Cezanne. \n\nA role for WIPI beta propellers in autophagy and neurodegeneration \nBy Prof. Dr. Tassula Proikas-Cezanne \nEberhard Karls University Tübingen · Interfaculty Institute of Cell Biology (IFIZ)
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-prof-dr-tassula-proikas-cezanne/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20231109T103000
DTEND;TZID=UTC:20231109T120000
DTSTAMP:20230906T074722Z
CREATED:20230602T104945Z
LAST-MODIFIED:20230906T074722Z
UID:10000020-1699525800-1699531200@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Dr. Emanuele Buratti
DESCRIPTION:Talk announcement for Dr. Emanuele Buratti \n\nAxon guidance genes are regulated by ALS associated TDP-43 and RGNEF genes through the rate of long-intron processing \nBy Dr. Emanuele Buratti \nInternational Centre for Genetic Engineering and Biotechnology
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-emanuele-buratti/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20231012T090000
DTEND;TZID=UTC:20231012T110000
DTSTAMP:20230906T074819Z
CREATED:20230602T104847Z
LAST-MODIFIED:20230906T074819Z
UID:10000019-1697101200-1697108400@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Dorothee Dormann
DESCRIPTION:Talk announcement for Dorothee Dormann
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-dorothee-dormann/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20231004T090000
DTEND;TZID=UTC:20231006T180000
DTSTAMP:20230627T070342Z
CREATED:20230615T073356Z
LAST-MODIFIED:20230627T070342Z
UID:10000016-1696410000-1696615200@crc1551.com
SUMMARY:SFB 1551 Annual Retreat
DESCRIPTION:Content is protected.
URL:https://crc1551.com/our-event/sfb-1551-annual-retreat-2/
LOCATION:Kloster Höchst\, Kirchberg 3\, Höchst im Odenwald\, 64739\, Germany
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20231002T090000
DTEND;TZID=UTC:20231002T113000
DTSTAMP:20230925T132711Z
CREATED:20230925T132711Z
LAST-MODIFIED:20230925T132711Z
UID:10000042-1696237200-1696246200@crc1551.com
SUMMARY:SFB 1551 Workshop - Science & Communication
DESCRIPTION:We are having a Science & Communication workshop on October 2\, 2023. \nTalks included in this workshop: \n“Natural Product research: a journey back to the future” \n“The heart is the central organ of the body\, but what about science?” \n“Investigating New Drug Options for Temozolomide-Resistant IDH1 Mutant Glioma” \n“Hydrogen’s Horizons: Harnessing Nature’s Hints and Novel Notions” \n 
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-science-and-communication/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20230924T080000
DTEND;TZID=UTC:20230928T170000
DTSTAMP:20230509T062257Z
CREATED:20230203T105152Z
LAST-MODIFIED:20230509T062257Z
UID:10000006-1695542400-1695920400@crc1551.com
SUMMARY:SPP 2191 annual meeting 2023
DESCRIPTION:Save the dates for our upcoming annual meeting in Dresden. \nSeptember 24 – 28\, 2023 \n  \nMore info on location\, registration and program will follow soon!
URL:https://crc1551.com/our-event/spp2191-annual-meeting-2023/
LOCATION:Rhineland-Palatinate
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20230914T090000
DTEND;TZID=UTC:20230914T110000
DTSTAMP:20230906T074757Z
CREATED:20230602T104734Z
LAST-MODIFIED:20230906T074757Z
UID:10000018-1694682000-1694689200@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Svenja Morsbach
DESCRIPTION:Talk announcement for Svenja Morsbach
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-svenja-morsbach/
LOCATION:Biocenter I\, EG 00.187\, Hanns-Dieter-Hüsch-Weg 15\, Mainz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20230824T090000
DTEND;TZID=UTC:20230824T110000
DTSTAMP:20230801T125717Z
CREATED:20230626T063436Z
LAST-MODIFIED:20230801T125717Z
UID:10000031-1692867600-1692874800@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Martin Girard
DESCRIPTION:Talk announcement of Martin Girard \n————————————————————————————————————————————————- \n*From lead to cells: digital alchemy\, multicomponent mixtures\, and chemical regulation* \nby Dr. Martin Girard \nMax-Planck-Institute for Polymer Research
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-martin-girard/
LOCATION:Biocenter I\, EG 00.187\, Hanns-Dieter-Hüsch-Weg 15\, Mainz
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20230627T180000
DTEND;TZID=UTC:20230627T193000
DTSTAMP:20230616T094618Z
CREATED:20230614T032011Z
LAST-MODIFIED:20230616T094618Z
UID:10000027-1687888800-1687894200@crc1551.com
SUMMARY:Public Outreach Event: Verjüngung ist möglich. Die neuesten Erkenntnisse der Zellbiologie
DESCRIPTION:Öffentlicher Vortrag von Nina Ruge\nNina Ruge / Prof. Dr. Dorothee Dormann (SFB 1551\, IMB/Johannes Gutenberg-Universität Mainz) / Prof. Dr. Peter Baumann (IMB/Johannes Gutenberg-Universität Mainz) / Clemens Hoch (Minister für Wissenschaft und Gesundheit des Landes Rheinland-Pfalz) / Moderation: Christof Niehrs (Gründungsdirektor und wissenschaftlicher Direktor\, IMB). \nWir laden Sie am Dienstag\, 27. Juni um 18:00 Uhr herzlich an das Institut für Molekulare Biologie (IMB) in Mainz ein\, wenn Nina Ruge sich in ihrem Vortrag „Verjüngung ist möglich. Die neuesten Erkenntnisse der Zellbiologie“ damit auseinandersetzt\, was wir heute schon – wissenschaftlich fundiert –  für ein gesundes Altern tun können.\nNina Ruge ist bekannt aus Formaten wie dem „heute journal“\, „heute Nacht“ und „Leute heute“ im ZDF\, und moderierte zahllose weitere Talkshows und TV-Magazine. Heute ist sie schwerpunktmäßig als Autorin tätig\, u.a. als Fachautorin für die ‚Zellbiologie des Alterns‘. Ihre beiden Bücher\, „Altern wird heilbar. Jung bleiben mit der Kraft der drei Zellkompetenzen“ (2020) und „Verjüngung ist möglich. Wissenschaftlich erforscht – was wirklich hilft“ (2021)\, entführen die Leser:innen in die spannende Welt der modernen Forschung zum Altern und zu „Longevity“. \nIm Anschluss an ihren Vortrag wird Frau Ruge mit den beiden Mainzer Forschenden Prof. Dr. Dorothee Dormann (SFB 1551 IMB/Johannes Gutenberg-Universität Mainz) und Prof. Dr. Peter Baumann (IMB/Johannes Gutenberg-Universität Mainz) und Minister Clemens Hoch (Minister für Wissenschaft und Gesundheit des Landes Rheinland-Pfalz) neueste Erkenntnisse der Alternsforschung und deren Bedeutung diskutieren. Moderiert wird die Veranstaltung von Prof. Dr. Christof Niehrs (Gründungsdirektor und wissenschaftlicher Direktor\, IMB). \nDie Veranstaltung ist eine Kooperation des Instituts für Molekulare Biologie (IMB) und des Centre for Healthy Ageing (CHA) in Mainz und wird unterstützt vom SFB 1361.\nVortrag und Diskussion werden auf Deutsch gehalten und richten sich an ein breites Publikum. \nDie Besucheranzahl ist begrenzt\, wir bitten daher um verbindliche Anmeldung bis zum 16. Juni hier
URL:https://crc1551.com/our-event/public-outreach-event-verjungung-ist-moglich-die-neuesten-erkenntnisse-der-zellbiologie/
LOCATION:Institute of Molecular Biology\, Ackermannweg 4\, Mainz
ATTACH;FMTTYPE=image/png:https://crc1551.com/wp-content/uploads/2023/06/Poster_Nina_Ruge_final_with_SFB1551_resized.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20230621T143000
DTEND;TZID=UTC:20230621T160000
DTSTAMP:20230607T053513Z
CREATED:20230602T102951Z
LAST-MODIFIED:20230607T053513Z
UID:10000017-1687357800-1687363200@crc1551.com
SUMMARY:Joint SFB 1551 & TRR 146 Seminar Series Event - Abhishek Singharoy
DESCRIPTION:Talk announcement of Abhishek Singharoy \n\n*Biophysics at the Dawn of Exascale Computers – The Age of Molecular Simulation Bots* \nAbstract:\nMolecular modeling of biomolecular assemblies exemplifies a disruptive area holding both promises and contentions. We will start with a brief story of simulating the first ever cell organelle in molecular details to find how nature has chosen survival fitness over efficiency of energy transfer as an evolutionary design . Despite such advances in exascale computing\, biophysical simulation continues to grapple with handling molecular diversity. So\, we will employ deep learning approaches often used in Google searches\, called the inception network\, to marry interaction signatures from alphafold models and proteomics analysis with predictable patient outcomes.  An application will highlight how molecular modeling is used at an industrial scale to de-risk vector-based vaccines for distribution across 194 countries. We will conclude by seeing how transient interactions are difficult to predict\, and path integrals with reinforcement learning offer a possible way to track diversity of dynamics.  \nby Assistant Prof. Abhishek Singharoy \nArizona State University \nSchool of Molecular Sciences
URL:https://crc1551.com/our-event/joint-sfb-1551-trr-146-seminar-series-event/
LOCATION:Minkowski Room\, Staudingerweg 7\, Mainz\, Germany
ATTACH;FMTTYPE=image/png:https://crc1551.com/wp-content/uploads/2023/06/Abhishek_graphical_abstract.png
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BEGIN:VEVENT
DTSTART;TZID=UTC:20230616T100000
DTEND;TZID=UTC:20230616T110000
DTSTAMP:20230602T103237Z
CREATED:20230509T061508Z
LAST-MODIFIED:20230602T103237Z
UID:10000015-1686909600-1686913200@crc1551.com
SUMMARY:Joint SFB 1551 & SFB 1361 Seminar Series Event - Matthias Altmeyer
DESCRIPTION:Talk announcement of Matthias Altmeyer \n\n*Dynamics and Functions of DNA Repair Compartments* \nAbstract: \nGenome stability is constantly challenged by reactive byproducts of\ncellular metabolism and environmental toxins. Dedicated repair pathways\nhave evolved to deal with DNA damage\, and their malfunctioning is\nassociated with human diseases such as cancer and neurodegeneration.\nElucidation of the hierarchy and temporal order in which DNA damagesensing\nproteins as well as signaling and repair factors assemble around\nDNA lesions has painted a complex picture of tightly regulated\nmacromolecular interactions that build specialized nuclear compartments\nto facilitate repair and maintain genome integrity. While many of the\nunderlying interactions\, e.g. between repair factors and damage-induced\nhistone modifications\, can be explained by lock-and-key or induced fit\nbinding models assuming fixed stoichiometries\, structurally less well\ndefined interactions\, such as the highly dynamic multivalent interactions\nimplicated in biomolecular condensate formation by phase separation\,\nalso participate in the formation of multi-protein assemblies at sites of\nDNA damage. In this seminar\, a summary and an update will be provided\non efforts to characterize and better understand the dynamics and\nfunctions of cellular DNA repair compartments and how they coordinate\nmaintenance of genome integrity in space and time. \n  \nby Prof. Dr. Matthias Altmeyer \nUniversity of Zurich \nDepartment of Molecular Mechanisms of Disease \n\nTalk_Announcement_Altmeyer
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event-matthias-altmeyer/
LOCATION:Seminar room 2nd floor\, Ackermannweg 4\, Mainz\, Germany
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BEGIN:VEVENT
DTSTART;TZID=UTC:20230503T090000
DTEND;TZID=UTC:20230505T133000
DTSTAMP:20230508T095021Z
CREATED:20230508T063445Z
LAST-MODIFIED:20230508T095021Z
UID:10000014-1683104400-1683293400@crc1551.com
SUMMARY:Gutenberg Workshop - Multivalent Interactions in Aging – Targets for Intervention?
DESCRIPTION:This workshop will bring together experts in molecular aging\, biopolymer interactions and polymer theory to discuss how non-deterministic\, multivalent and disordered biomolecular interactions contribute to cellular function. While multivalent interactions come with a certain degree of resilience to perturbation\, it is well known that disturbances of such interactions contribute to aging and devastating degenerative diseases. At this workshop\, participants will discuss our current understanding of non-deterministic assemblies driven by disorder and multivalency and possible pathways towards the design of new and innovative intervention strategies to treat age-associated diseases. \n  \nConfirmed Speakers: \nSimon Alberti\, TU Dresden (GER) \nThomas Boothby\, University of Wyoming (USA) \nAlexander Buell\, DTU (Denmark) \nDella David\, Babraham (UK) \nLin Guo\, Thomas Jefferson University (USA) \nMartin Hetzer\, ISTA (Austria) \nTuomas Knowles\, University of Cambridge (UK) \nChiu Fan Lee\, Imperial College (UK) \nSua Myong\, Johns Hopkins (USA) \nRohit Pappu\, Washington University in St Louis (USA) \nKausik Si\, Stowers Institute (USA) \nLiesbeth Veenhoff\, ERIBA (Netherlands) \nSusanne Wegmann\, DZNE (GER) \nScientific Organizers: Dorothee Dormann and Edward Lemke
URL:https://crc1551.com/our-event/gutenberg-workshop-multivalent-interactions-in-aging-targets-for-intervention/
LOCATION:Kloster Wasem\, Edelgasse 15\, Ingelheim\, Germany
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BEGIN:VEVENT
DTSTART;TZID=UTC:20230502T100000
DTEND;TZID=UTC:20230502T180000
DTSTAMP:20230512T071014Z
CREATED:20230417T104033Z
LAST-MODIFIED:20230512T071014Z
UID:10000010-1683021600-1683050400@crc1551.com
SUMMARY:SFB 1551 Seminar Series Event - Lin Guo & Rohit Pappu
DESCRIPTION:Professors Lin Guo and Rohit Pappu will visit for a talk on May 2\, 2023. \n\n*Hidden complexities of condensates formed by simple systems* \nAbstract: \nApplication of the physics of associative macromolecules has led to growing recognition that condensates\, even of relatively simple systems\, form via hierarchies of processes governed by sequence-encoded molecular grammars that go beyond LLPS. The talk will present data and results from experiments and simulations that highlight the importance of phase separation coupled to percolation for systems governed by homotypic interactions\, and the relevance of the coupling between microphase and macrophase separation in systems where homotypic and heterotypic interactions work together. Broader implications for complex multicomponent systems will also be discussed. \nby Professor Rohit Pappu \nWashington University in St. Louis \nDepartment of Biomedical Engineering \n  \n*Reversing Aberrant Phase Transitions of ALS-linked Disease Protein: FUS* \nAbstract: \nLiquid-liquid phase separation (LLPS) mediates the formation of diverse membraneless organelles\, such as stress granules (SGs) in the cytoplasm. Despite clear biological utility\, dysregulated liquid-liquid phase separation can be detrimental. For example\, phase-separated stress granules enrich RNA-binding proteins (RBPs)\, such as TDP-43 and FUS\, which have an intrinsic tendency to form fibrils that are closely tied to fatal neurodegenerative disorders\, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Therefore\, it is important to understand how cells regulate the liquid-liquid phase separation of biomolecular condensates\, which includes maintaining beneficial phases and simultaneously preventing pathological phase separation and fibrillization. As RNA-binding proteins localize mainly in the nucleus\, the phase separation of FUS and TDP-43 can be regulated by both nuclear import receptors and short RNAs. For example\, we found that phase separation of FUS can be regulated by Karyopherinβ2 (Kapβ2)\, which recognizes the proline/tyrosine–nuclear localization signal (PY-NLS) at the C-terminus of FUS protein. On the other hand\, phase separation of TDP-43 can be regulated by the Importina/Karyopherinb1 complex\, which binds to the canonical NLS of TDP-43. In vivo\, Kapβ2 prevents FUS accumulating in stress granules\, restores nuclear FUS localization and function. By preventing and reversing aberrant FUS phase transition and cytoplasmic localization\, Kapβ2 is able to rescue neurodegeneration caused by disease-linked FUS. Our results indicate that regulating FUS LLPS by nuclear import receptors could be potential therapeutic strategy for ALS/FTD. \nby Professor Lin Guo \nThomas Jefferson University \nDepartment of Biochemistry and Molecular Biology \nLinGuo_RohitPappu_Talk_Announcement_02052023
URL:https://crc1551.com/our-event/sfb-1551-seminar-series-event/
LOCATION:Biocenter I\, EG 00.187\, Hanns-Dieter-Hüsch-Weg 15\, Mainz
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BEGIN:VEVENT
DTSTART;TZID=UTC:20230425T123000
DTEND;TZID=UTC:20230425T190000
DTSTAMP:20230418T105712Z
CREATED:20230227T074510Z
LAST-MODIFIED:20230418T105712Z
UID:10000008-1682425800-1682449200@crc1551.com
SUMMARY:RMU-RNA Salon - "Genomics approaches in RNA biology"
DESCRIPTION:10. Mini-Symposium\n“RNA condensates & computational biology”\n  \n\nKeynote speaker \nDorothee Dormann (IMB/JGU Mainz) – “RBP phase transitions & neurodegeneration” \nGerhard Hummer (MPI Frankfurt) – “modelling of disorder & phase separation” \n\nInvited speaker \nBernhard Hampölz (MPI Frankfurt) – ” phase separation & nuclear envelope dynamics” \nStefan Müller (GU Frankfurt) – “RNA condensates & protein quality control” \nMichaela Müller-McNicoll (GU Frankfurt) – “subcellular architecture & gene expression control” \nLukas Stelzl (IMB Mainz) -“RBP recognition by condensates & simulations” \nKathi Zarnack (GU Frankfurt) – “RNA regulation & P-bodies” \n\nSubmit an abstract for a short talk or poster! \nRegistration is free at https://bit.ly/3SftutA \n10. RMU-RNA Salon – Flyer \n  \nFurther information: RMU-RNA-Salon@uni-frankfurt.de
URL:https://crc1551.com/our-event/rmu-rna-salon-genomics-approaches-in-rna-biology/
LOCATION:Frankfurt Institute for Advanced Studies\, Riedberg Campus\, Room 0.100\, Frankfurt\, Germany
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BEGIN:VEVENT
DTSTART;TZID=UTC:20230424T160000
DTEND;TZID=UTC:20230424T210000
DTSTAMP:20230418T104753Z
CREATED:20230414T061715Z
LAST-MODIFIED:20230418T104753Z
UID:10000009-1682352000-1682370000@crc1551.com
SUMMARY:Picture a Scientist - an interactive workshop to raise awareness for diversity
DESCRIPTION:Together with the SFB 1361 and GenEvo we are hosting an afternoon workshop to focus on empowerment and to raise awareness for diversity and against discrimination in order to promote a gender- and diversity-sensitive work and research culture. \nScience careers are about the science\, and they’re also about the people – including how people think about\, and treat\, each other. We all want a science system that rewards good ideas and good research and which treats everyone fairly. We also as a group have experienced or suspected (or maybe remained oblivious to) the reality that science systems are not always operating fairly for everyone. And when we lose good ideas and good people to injustices\, we collectively hurt the quality of the science and our own ethics and values. Let’s look together at some of these themes that we inherited from the past and still live with today in order to change the system for the better. \nWe would like to invite all group leaders\, postdocs and PhD students to join us for a productive discussion and lively exchange of views at our first event on Monday\, April 24 2023 4.15-9 pm at IMB\, followed by dinner. What we have planned is: \n\nan interactive workshop led by Prof. Heather Hofmeister\, looking at patterns in our own and others’ experiences in Germany and comparing German academic power structures to those in other countries\, followed by\nthe screening of the documentary feature-length film from 2020 called “Picture a scientist” about the experiences of underrepresented groups in several fields of science\, and afterwards\,\nwork out conclusions and solutions together – and then we get to the pizza!\n\n  \nAbout the moderator \nHeather Hofmeister is a Professor\, Speaker\, Leader\, Coach\, Writer\, and Researcher. She holds a full Professorship for Sociology of Work at the Goethe University\, Frankfurt and is co-director of the Center for Leadership and Behavior in Organizations (CLBO). She researches and speaks internationally on topics in work\, gender\, diversity\, leadership\, careers\, and science\, using a life course and international comparative perspective. \nHofmeister served three years as Vice-Rector at RWTH Aachen University as the first woman in the Rectorate from age 35 and held the first professorship of Sociology with the specialty in Gender and Life Course Research there. In Frankfurt\, she served as Chair of the Department of Sociology\, Chair of the Board of Examiners\, and Dean of Studies at the Goethe University Faculty of Social Sciences. She has led and currently leads large interdisciplinary research projects as PI\, serves on the Board of Trustees of the Technical University of Munich (TUM)\, and served on the Board of Trustees at the University of Bamberg. Hofmeister is a trained coach\, and she facilitates groups and classes of up to 800. Hofmeister came to Germany from the USA with a Ph.D. from Cornell University in 2002. https://www.heather-hofmeister.com/ \n  \nAbout the Movie: Picture a Scientist  \nWho actually does science? And why is it often still “the male scientist” who wins prestige in our imagination? In PICTURE A SCIENTIST\, a female biologist\, a female chemist and a female geologist take on these questions and lead the audience on a journey through the experiences of their academic careers. \nUsing their biographies as examples\, the film deals with a variety of problems that are also relevant in the German university system. These include sexualised harassment in everyday university and research life\, exclusion mechanisms and unequal treatment\, multiple discrimination and the role of leaders and institutions. The film shows the achievements of the past decades\, but also makes visible the resistance women have to face at every level of the academic world. It has a disturbing\, outrageous effect – and calls for action. \n  \n\nThis workshop is open to to all members in our network(s). You may register by filling out our online form here: https://forms.office.com/e/900buyAJbv  Registration will come on a first-come\, first-served basis.
URL:https://crc1551.com/our-event/picture-a-scientist-an-interactive-workshop-to-raise-awareness-for-diversity/
LOCATION:Institute of Molecular Biology\, Ackermannweg 4\, Mainz
ATTACH;FMTTYPE=image/jpeg:https://crc1551.com/wp-content/uploads/2023/04/PictureAScientist-FB-2d2-1.jpg
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BEGIN:VEVENT
DTSTART;TZID=UTC:20230316T090000
DTEND;TZID=UTC:20230316T123000
DTSTAMP:20230322T105107Z
CREATED:20230223T071023Z
LAST-MODIFIED:20230322T105107Z
UID:10000007-1678957200-1678969800@crc1551.com
SUMMARY:General Assembly of the SFB 1551
DESCRIPTION:This will be the SFB 1551 ‘s first general assembly for all members and associates where we will be discussing general topics such as budgets\, seminar talks and planned retreats/summer schools. \n\nWe have 3 talks planned by PIs who’d like to join our network: \nCarla Schmidt (Biochemistry) \nJan Padeken (IMB) \nShikha Dhiman (Chemistry)
URL:https://crc1551.com/our-event/general-assembly-of-the-crc-1551/
LOCATION:Schulz-Horner Gebäude\, C02\, Duesbergweg\, Mainz\, 55128\, Germany
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BEGIN:VEVENT
DTSTART;TZID=UTC:20230313T140000
DTEND;TZID=UTC:20230313T160000
DTSTAMP:20230417T123802Z
CREATED:20230417T123802Z
LAST-MODIFIED:20230417T123802Z
UID:10000012-1678716000-1678723200@crc1551.com
SUMMARY:TRR 319 - RMaP and SFB 1551 Seminar - Frederic Allain & Elizabeth Hartland
DESCRIPTION:Talk announcement for the seminar of TRR 319 – RMaP and the SFB 1551 \n\n*FUS RNA binding\, phase separation and aging as studied by NMR spectroscopy* \nby Prof. Dr. Frederic Allain\, Institute of Biochemistry \nETH Zurich\, Switzerland \n  \n*“Legionella\, host cell RNA and immunometabolism* \nby Prof. Elizabeth Hartland\, Monash University \nDirector and CEO\, Hudson Institute of Medical Research\nFaculty of Medicine\, Nursing and Health Sciences\, Australia
URL:https://crc1551.com/our-event/trr-319-rmap-and-sfb-1551-seminar-frederic-allain-elizabeth-hartland/
LOCATION:IPBW Seminarraum I EG 00.111\, Staudingerweg 5\, Mainz
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