SFB 1551

SFB 1551 Student Seminar Series Event - Katrin Debrich & Mahesh Yadav
2024-09-24 12:30 - 13:30 UTC | Biocenter 2, Hanns-Dieter-Hüsch-Weg 17, Mainz
Phase separation of IM30, a protein involved in membrane dynamics by Katrin Debrich

Advancing the characterization of intrinsically disordered proteins by Mahesh Yadav

Liquid Matter Conference 2024
2024-09-22 08:00 - 2024-09-27 17:00 (Europe/Amsterdam) | Alte Mensa, Johann-Joachim-Becher-Weg 3-5, Mainz, 55128, Germany
This conference is organized by the Liquids Section of the Condensed Matter Division of the European Physical Society.
The aim of the conference is to bring together scientists working on the liquid state of matter. This rapidly growing field includes the physics, chemistry, biology, and chemical engineering of liquid matter as well as various applied research areas in the chemical, pharmaceutical and food industries.
The conference will consist of plenary lectures, topical symposia with keynote lectures and contributed oral presentations, and poster sessions. The plenary and keynote lectures will be streamed. All speakers will be on site.
More information (including topics, invited speakers, registration fees, etc.) can be found on the event website here.
(The above information was found on this page.)

SFB 1551 Seminar Series Event - Dirk Schneider & Nadja Hellmann
2024-09-19 10:30 - 11:30 UTC | Rhineland-Palatinate
Isolating and characterizing proteins for in vitro condensate formation might be problematic!
Have you ever worked with isolated proteins? Most work in our group involves the isolation of (typically recombinantly produced) proteins plus their biophysical characterization. During this work, we encountered several problems associated with the insolation of tagged proteins and/or with their biophysical characterization. We have therefore decided to discuss some problems that typically occur but are often ignored “hands on”. We will focus on the isolation of tagged proteins plus their characterization via CD spectroscopy and/or dynamic light scattering. We will use examples from our own research with a condensate-forming protein to highlight some problems and pitfalls.

SFB 1551 Research Data Management Workshop of image data 2024
2024-09-03 14:00 - 16:00 UTC | Biocenter 1 – Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 15, Mainz, Rhineland-Palatinate, 55128, Germany
Content is protected.

SFB 1551 Seminar Series Event - Prof. Dr. Andrea Musacchio
2024-09-02 14:00 - 17:00 UTC | Rhineland-Palatinate
1st talk at 14:00: “Feedback control of mitosis in the context of the kinetochore”
2nd talk at 15:30: “On the role of liquid-liquid phase separation in the establishment of biomolecular condensates”

By Prof. Dr. Andrea Musacchio
Max Plank Institute of Molecular Physiology Dortmund · Department of Mechanistic Cell Biology

SFB 1551 Research Data Management Workshop 2024 - session A
2024-08-30 09:00 - 12:00 UTC | Biocenter 1 – Johannes Gutenberg University, Hanns-Dieter-Hüsch-Weg 15, Mainz, Rhineland-Palatinate, 55128, Germany

SFB 1551 Seminar Series Event - Axel Methner
2024-08-29 10:30 - 11:30 UTC | Rhineland-Palatinate
Talk announcement for Axel Methner

SFB 1551 Seminar Series Event - Prof. Dr. Christian Schlieker
2024-07-08 11:00 - 12:00 UTC | Rhineland-Palatinate
“(Dis)connecting Aberrant Nuclear Condensates and Neurological Disorders”
By Prof. Dr. Christian Schlieker
Yale University · Department of Molecular Biophysics & Biochemistry
View Abstract

SFB 1551 Seminar Series Event - Dr. Tanja Mittag & Prof. Kresten Lindorff-Larsen
2024-07-01 09:00 - 12:00 UTC | Rhineland-Palatinate
“Driving forces for phase separation, material properties and aging processes of condensates”
By Dr. Tanja Mittag
St. Jude Children’s Research Hospital · Department of Structural Biology
View abstract
“Towards structure prediction and design of disordered proteins”
By Prof. Dr. Kresten Lindorff-Larsen
Linderstrøm-Lang Centre for Protein Science · Structural Biology and NMR Laboratory
View abstract

SFB 1551 Seminar Series Event - Prof. Dr. Matthias Ballauff
2024-06-20 10:30 - 11:30 UTC | Rhineland-Palatinate
“Polyelectrolytes and Biological Systems: A Charged Relationship”
By Prof. Dr. Matthias Ballauff
Freie Universität Berlin · Institut für Chemie und Biochemie
View Abstract

Workshop with Prof. Heather Hofmeister (Joint Event with GenEvo, 4R, SFB1361, and SFB1551)
2024-06-06 09:30 - 13:00 UTC | IMB Seminar Room, Ackermannweg 4, Mainz, 55128, Germany
We are pleased to invite you to participate in a workshop with Prof. Heather Hofmeister entitled “Communication competencies in intercultural and intergenerational teams”.
This half-day workshop will focus on how to navigate conversations and differences in understanding each other based on different gender, cultural backgrounds, and expectations and locations in the power hierarchy and will be specifically designed for PhD students & early postdoctoral researchers from 4R, GenEvo, SFB 1361, and SFB 1551.
The workshop will be held on Thursday, June 6th, from 9:30 to 13:00, please mark your calendars!

EMBO | EMBL Symposium: Cellular mechanisms driven by phase separation
2024-05-14 08:00 - 2024-05-17 17:00 UTC | EMBL, Meyerhofstraße 1, Heidelberg, 69117
This conference will take place at EMBL Heidelberg, with the option to attend virtually.
Registration is now open! Click the link below to register for on-site or virtual attendance!
Symposium overview
Phase separation is emerging as a common biophysical basis underlying many important cellular functions. This conference will bring together scientists from soft matter, polymer physics, molecular biology, structural biology, and cell and developmental biology to study condensates in biology and disease. Goals are

to increase the awareness how important phase separation is for our understanding of many biological processes
to explore the large repertoire of new tools generated by other disciplines that are ripe to be applied to complex problems related to phase separation
to close the gap in transdisciplinary training to tackle the role of phase separation in biology

For more information please visit https://www.embl.org/about/info/course-and-conference-office/events/ees24-06/#vf-tabs__section-overview

SFB 1551 Seminar Series Event - Sina Wittmann
2024-05-02 10:30 - 11:30 UTC | Rhineland-Palatinate
Talk announcement for Sina Wittmann
Title: Protein condensation in the presence of nucleic acids
In the cell, many protein condensates form by nucleic acid binding proteins. This is true in the cytoplasm as well as in the nucleus. An example of the former would be RNA-binding proteins forming stress granules and of the latter the nucleolus. However, different physical phenomena can be behind these interactions. I will discuss different approaches of how to observe them experimentally.

SFB 1551 Seminar Series Event - Prof. Dr. Tassula Proikas-Cezanne
2024-04-25 10:30 - 11:30 UTC | Rhineland-Palatinate
Talk announcement for Prof. Dr. Tassula Proikas-Cezanne.

A role for WIPI beta propellers in autophagy and neurodegeneration
By Prof. Dr. Tassula Proikas-Cezanne
Eberhard Karls University Tübingen · Interfaculty Institute of Cell Biology (IFIZ)

SFB 1551 Seminar Series Event - Prof. Dr. Jörg Höhfeld
2024-04-11 10:30 - 11:30 UTC | Rhineland-Palatinate
Talk announcement for Prof. Dr. Jörg Höhfeld.

Maintaining the proteome under mechanical stress – from mechanisms to pathology
By Prof. Dr. Jörg Höhfeld
Universität Bonn · Institut für Zellbiologie
Abstract from Prof. Höhfeld:
Organismal survival depends on the ability to maintain functional protein networks even under conditions that threaten protein integrity. Cells in multicellular organisms are constantly exposed to stress resulting from mechanical forces. In this situation, protein homeostasis relies on a chaperone machinery that is organized by the co-chaperone BAG3. The BAG3-machinery recognizes force-unfolded cytoskeleton proteins and mediates their disposal through chaperone-assisted selective autophagy (CASA). In addition, BAG3 interacts with components of the Hippo and mTOR signalling pathways to stimulate transcription and translation. This is important for compensating degradation during cytoskeleton maintenance. In agreement with its essential role under mechanical stress, BAG3 deficiency causes severe muscle weakness in children and contributes to heart failure, a leading cause of mortality in industrialized nations. Here, we discuss the mode of action of the BAG3-machinery and its force-dependent regulation and pathophysiological relevance.

SFB 1551 Seminar Series Event - Prof. Dr. Ralf Metzler
2024-03-14 10:30 - 11:30 UTC | Rhineland-Palatinate
Talk announcement for Prof. Dr. Ralf Metzler.

“Long-ranged correlated processes in disordered systems”
By Prof. Dr. Ralf Metzler
Universität Potsdam
Abstract from Prof. Metzler:
Stochastic processes with long-ranged, power-law correlations naturally emerge in systems such as Rouse polymers or single-file systems, when all degrees of freedom are integrated out, apart from the (tracer) particle of interest. In non-equilibrium situations, the resulting overdamped dynamics corresponds to Mandelbrot’s fractional Brownian motion (FBM).
This talk will address some peculiar behaviours of FBM when subject to confinement in box potentials as well as sub- or superharmonic external potentials. Specifically, it will be argued why superdiffusive FBM may be a good (polymer) model for growing serotonergic fibres in the mammalian brain.
In disordered environments it will be shown how non-Gaussian displacement density functions emerge and subtly depend on how the dynamics is introduced. This is achieved by stochastic-diffusivity models connected with long-range dependent noise. Moreover, it will be discussed how time-dependent critical exponents can be introduced in this formalism.
Finally, amoeba systems will be introduced in which the displacement density function appears to converge to a non-Gaussian, Laplace density.

SFB1551 Winter School
2024-03-04 09:00 - 2024-03-07 17:00 UTC | Kurpark-Hotel, Schloßplatz 1-4, Bad Dürkheim, 67098, Germany

SFB 1551 Seminar Series Event - Prof. Dr. Konstanze Winklhofer
2024-02-22 10:30 - 11:30 UTC | Rhineland-Palatinate
Talk announcement for Prof. Dr. Konstanze Winklhofer

“Linear polyubiquitin as a regulator of phase transitions in signaling and protein quality control”
By Prof. Dr. Konstanze Winklhofer
Ruhr-Universität Bochum

SFB 1551 Seminar Series Event - Prof. Dr. Andela Saric
2024-02-06 10:30 - 11:30 UTC | Rhineland-Palatinate
Talk announcement for Prof. Dr. Andela Saric.

“Protein assemblies that split and merge cells across evolution”
By Prof. Dr. Andela Saric
Institute of Science and Technology Austria
Abstract from Prof. Saric:
I will present our recent research on the computational modelling of energy-consuming protein filaments that dynamically reshape and cut cells across evolution. I will first discuss the physical mechanism of ESCRT-III filaments that drive cell division and cell trafficking in archaea and eukaryotes. I will then discuss the physical mechanism behind the dynamic self-organisation of biochemically active FtsZ filaments in the early stages of bacterial division. Throughout, I will present the comparisons of our models to in vitro and in vivo data. I will finish up with our recent thoughts on the shapes of symbiotic organisms that might have led to the emergence of eukaryotes.

Workshop with Prof. Heather Hofmeister (Joint Event with GenEvo, 4R, SFB1361, and SFB1551)
2024-02-01 15:30 - 19:30 UTC | Rhineland-Palatinate
We are pleased to invite you to participate in a workshop with Prof. Heather Hofmeister entitled “Navigating challenging conversations within power hierarchies”.
This half-day workshop will focus on how to navigate “difficult” conversations and differences in understanding each other based on different gender, cultural backgrounds, and expectations and locations in the power hierarchy and will be specifically designed for PhD students & early postdoctoral researchers from 4R, GenEvo, SFB 1361, and SFB 1551.
The workshop will be held on Thursday, February 1st, from 15:30 to 19:00, followed by a pizza dinner. Please mark your calendars! Official registration for the workshop will follow in January. Participation will be credited with 2 hours (towards your IPP certificate).
To ensure that the workshop also addresses any more specific questions or requests, please feel free to share them with us in advance using this link (anonymous).

SFB 1551 Seminar Series Event - Dorothee Dormann
2024-01-11 09:00 - 11:00 UTC | Rhineland-Palatinate
Talk announcement for Dorothee Dormann.

Experimental methods to study aggregation-prone RNA-binding proteins (part 2)

SFB 1551 Seminar Series Event - Prof. Dr. Christoph Weber
2023-12-14 11:00 - 12:00 (Europe/Amsterdam) | Rhineland-Palatinate
Talk announcement for Prof. Dr. Christoph Weber.

Christmas Colloquium (Jointly organised by SFB1361, SFB1551, GenEvo, 4R-RTG)
2023-12-13 16:00 UTC | IMB Seminar Room, Ackermannweg 4, Mainz, 55128, Germany
We are delighted to invite you all to a Christmas Colloquium on Wednesday, 13 December 2023 starting at 16:00, and followed by dinner and merriment! This is a joint event organised by SFB 1361, SFB 1551, GenEvo, and 4R-RTG.

There will be an interesting talk given by a 2023 Alexander von Humboldt Professorship recipient, Prof. Hanna Kokko. She is a theoretical evolutionary biologist and is currently based in JGU carrying out research to better understand the interaction between evolutionary and ecological processes.

The event is open to all members of the SFB 1361, SFB 1551, GenEvo, and 4R-RTG. So, mark your calendars and come join us in the IMB seminar room for the talk and get-together afterwards!

Postponed - SFB 1551 Seminar Series Event - Prof. Dr. Tassula Proikas-Cezanne
2023-12-07 10:30 - 11:30 UTC | Rhineland-Palatinate

SFB 1551 Seminar Series Event - Dr. Emanuele Buratti
2023-11-09 10:30 - 12:00 UTC | Rhineland-Palatinate
Talk announcement for Dr. Emanuele Buratti

Axon guidance genes are regulated by ALS associated TDP-43 and RGNEF genes through the rate of long-intron processing
By Dr. Emanuele Buratti
International Centre for Genetic Engineering and Biotechnology

SFB 1551 Seminar Series Event - Dorothee Dormann
2023-10-12 09:00 - 11:00 UTC | Rhineland-Palatinate
Talk announcement for Dorothee Dormann

SFB 1551 Annual Retreat
2023-10-04 09:00 - 2023-10-06 18:00 UTC | Kloster Höchst, Kirchberg 3, Höchst im Odenwald, 64739, Germany

SFB 1551 Workshop - Science & Communication
2023-10-02 09:00 - 11:30 UTC | Rhineland-Palatinate
We are having a Science & Communication workshop on October 2, 2023.
Talks included in this workshop:
“Natural Product research: a journey back to the future”
“The heart is the central organ of the body, but what about science?”
“Investigating New Drug Options for Temozolomide-Resistant IDH1 Mutant Glioma”
“Hydrogen’s Horizons: Harnessing Nature’s Hints and Novel Notions”

SPP 2191 annual meeting 2023
2023-09-24 08:00 - 2023-09-28 17:00 UTC | Rhineland-Palatinate
Save the dates for our upcoming annual meeting in Dresden.
September 24 – 28, 2023

More info on location, registration and program will follow soon!

SFB 1551 Seminar Series Event - Svenja Morsbach
2023-09-14 09:00 - 11:00 UTC | Biocenter I, EG 00.187, Hanns-Dieter-Hüsch-Weg 15, Mainz
Talk announcement for Svenja Morsbach
