Post-translational modifications (PTMs) play an important role in modifying protein function and cell physiology, but...
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Signal transmission between neurons takes place at specifically designed contact sites called synapses. Successful transmission...
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The Integrated Research Training Group (IRTG) is a structured PhD programme that aims to train...
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Protein aggregation into fibres inside cells is an ever-present process associated with human disease, but...
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DNA is the largest biopolymer in nature with a length of up to 10Â cm (human...
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Whereas our genome is localized in the membrane-enclosed nucleus, membrane-less compartments within the nucleus further...
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The post-translational modifiers ubiquitin and SUMO, two small, conserved proteins known for their ability to...
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The compaction of our two-meter-long genome into a confined micron-sized nuclear volume creates numerous challenges...
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Biological systems often rely on switch-like all-or-nothing responses. These regulatory switches are based on feedback...
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Targeted protein degradation can be enhanced by compartmentalizing protein degradation through the formation of proteolytic...
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Block co-polymers are comprised of multiple homopolymer regions that enable the design of polymer materials...
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Whereas in vitro studies (here referring to studies using purified components) can provide molecular insights,...
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Germ cells are characterized by various membrane-less organelles, collectively named germ granules. These contain many...
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The long-term goal of this project is to establish biopolymer-based protonuclei compartments as a viable...
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In this project, the dynamics of light-activated formation of condensates of splicing regulatory proteins will...
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In this project, we will establish a service platform for the production and engineering of...
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The coordination module will be supervised by the designated spokesperson and the designated management committee....
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The stabilization, remodelling, and repair of biological membranes are critical tasks by which eukaryotic cells...