4 – 6 March, 2026
Mainz, Germany
08:30 Arrival / Registration
09:00 - 09:15 Welcome
09:15 - 09:30 ST1: Dirk Schneider (JGU Mainz, DE) Structural plasticity of a bacterial ESCRT-III protein
09:30 - 09:45 ST2: Tiemei Lu (University of Oxford, UK) Controlling Multiphase Coacervate Wetting and Self-Organization by Interfacial Proteins
09:45 - 10:15 Talk: Andreas Herrmann (DWI Leibniz, DE) Polymer Mechanochemistry enables the Activation of Drugs, Proteins and Nucleic Acids by Biocompatible Ultrasound
10:15 - 10:45 Coffee-Break
10:45 - 11:15 Talk: Ben Schuler (University of Zurich, CH) Probing the Rapid Interaction Dynamics of Charged Disordered Proteins
11:15 - 11:30 ST3: Ananya Chakravarti (Princeton University, US) Accurate prediction of thermoresponsive phase behavior of disordered proteins
11:30 - 12:00 Talk: Birthe Kragelund (University of Copenhagen, DK) Opposites Attract - Charges in Protein Complexes
12:00 - 14:00 Lunch
14:00 - 14:30 Talk: Chiu Fan Lee (Imperial College London, UK) The synaptonemal complex assembles between meiotic chromosomes by wetting
14:30 - 14:45 ST4: Filipe Viana Ferreira (Nanyang Technological University, SG) Nanoscale Wetting and Mechanical Characterization of Peptide Coacervates on Supported Lipid Bilayers by Atomic Force Microscopy
14:45 - 15:00 ST5: Alexander von Appen (MPI Molecular Cell Biology and Genetics, Dresden, DE) A protein-DNA surface hydrogel mechanically reinforces the cell nucleus and protects the genome
15:00 - 15:30 Poster Teasers I
15:30 - 16:00 Coffee-Break
16:00 - 16:15 ST6: Brandon Malady (University of Texas at Austin, US) Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks
16:15 - 16:45 Talk: Shasha Chong (California Institute of Technology, US) Decoding Condensate Composition Reveals Tunable Interactomes and Functions of Intrinsically Disordered Proteins
16:45 - 17:15 Poster Teasers II
17:15 - 17:45 Break
17:45 - 18:00 ST7: Tsvetomir Ivanov (MPI for Polymer Research, Mainz, DE) Biomimetic Minimal Peptide Coacervates for Biocatalysis
18:00 - 18:30 Talk: Iva Pritišanac (Helmholtz, Munich, DE) Decoding Intrinsic Protein Disorder. From Proteome-Scale Maps to Condensate Specificity
19:00 - 20:30 Dinner
20:30 - 23:00 Networking & Discussion
09:30 - 10:00 Poster Set-up
10:00 - 10:30 Brunch starts
10:30 - 11:30 Poster Session with Brunch (A)
11:30 - 11:45 Group Picture
11:45 - 12:45 Poster Session with Brunch (B)
12:45 - 14:00 Continued Brunch
14:00 - 14:30 Talk: Sua Myong (Boston Children's Hospital, Harvard Medical School, US) FUS nanoclusters are a distinct state within the dilute phase
14:30 - 14:45 ST8: Saskia Hutten (JGU Mainz, DE) The NLS region of TDP-43 is crucial for its cellular localization and phase separation behavior
14:45 - 15:00 ST9: Rodrigo Dillenburg (JGU Mainz, DE) Differential conformational expansion of NUP98-HOXA9 oncoprotein from nanosized assemblies to macrophases
15:00 - 15:30 Talk: Ashutosh Chilkoti (Duke University, US) Synthetic Biomolecular Condensates for Biology and Medicine
15:30 - 16:00 Coffee-Break
16:00 - 16:30 Talk: Anđela Šarić (Institute of Science and Technology, AT) Mortal Polymers in Cells
16:30 - 16:45 ST10: Aida Naghilou (Medical University of Vienna, AT) Scanning probe microscopy for elucidating the rheological properties of biomolecular condensates during gelation and rejuvenation
16:45 - 17:15 Talk: Dora Tang (Saarland University, DE) Engineering synthetic condensate structure and dynamics: macromolecular control and compartment-driven feedback
17:15 - 17:45 Break
17:45 - 18:00 ST11: Iris Smokers (MPI for the Physics of Complex Systems, Dresden, DE) Selective ion binding and uptake shape the microenvironment of biomolecular condensates
18:00 - 18:15 ST12: Johann Fritzen (JGU Mainz, DE) Protonuclei: Synthetic DNA condensates explore protein phase separation
18:15 - 18:45 Talk: Jan van Hest (Eindhoven University of Technology, NL) Architectural control in polymer-based artificial cells.
18:45 - 19:00 Announcement of poster award finalists
19:00 - 20:15 Dinner
20:15 - 21:00 Networking & Discussion
Poster Review with Invited Speakers and Finalists
09:00 - 09:05 Intro
09:05 - 09:20 ST13: Michael te Vrugt (JGU Mainz, DE) Pattern formation in biological condensates
09:20 - 09:35 ST14: Jan Padeken (IMB Mainz, DE) Promoter and Gene-Body RNA-Polymerase II co-exist in partial demixed condensates
09:35 - 10:05 Talk: Simon Alberti (TU Dresden, DE) Kinetic Solubility as a Framework for Control of Multivalence in Living Cells
10:05 - 10:45 : Coffee Break
11:00 - 11:15 ST15: Adrian John Pinto (JGU Mainz, DE) Symmetry of loop extrusion by dimeric SMC complexes is tension dependent
11:15 - 11:30 ST16: Benjamin Frühbauer (ETH Zurich, CH) Condensation of satellite DNA by the disordered protein D1 safeguards nuclear mechanostability
11:30 - 12:00 Talk: Frank Jülicher (MPI for the Physics of Complex Systems, Dresden, DE) Active processes in condensates and droplets
12:00 - 13:30 Lunch
13:30 - 14:00 Talk: Jeanne Stachowiak (University of Texas at Austin, US) Intrinsic disorder as an organizing principle for biological membranes
14:00 - 14:15 ST17: Art Hoti (Leiden University, NL ) The missing link between biomolecular condensates and amyloid fibrils
14:15 - 14:30 ST18: Sarah Doerdrechter- Kinkley (MPI for Molecular Genetics, Berlin, DE) PHF13 Undergoes Phase Transitions via Differential Oligomerization to Modulate Chromatin Association and Function
14:30 - 15:00 Talk: Danfeng Cai (Johns Hopkins Bloomberg School of Public Health, US) Rainbow Nucleus Charts Dynamic Interactome of Membrane-less Organelles
15:00 - 15:15 Closing Remarks & Poster awards
15:30 - 16:30 Discussion & Coffee
POSTER LIST
| Num. | Name | Surname | Poster Tittle | Pesentation session |
| 1 | Zahra | Akbari | In silico membrane reshaping by molecular condensate | Teaser (I) / Poster (A) |
| 2 | Lucia | Baltz | Contact dynamics in MUT-16 condensate from atomistic molecular dynamics | Poster (A) |
| 3 | Tika Ram | Bhandari | Helical Cooperativity and Conformational Dynamics Driving Monomer Stabilization and Oligomerization in ESCRT-III Proteins | Poster (A) |
| 4 | Johanna | Buck | Mixing Martinis with synovial fluids: coarse grained models of complex polymer systems | Teaser (I) / Poster (A) |
| 5 | Xinxiang | Chen | Dilute but dense – Reversible crosslinking enables water-rich (bio)polymer condensates | Poster (A) |
| 6 | Mark | Chen | Dissecting DNA repair condensates through direct labeling of endogenous IDPs | Teaser (I) / Poster (A) |
| 7 | Francesca | Conte | The phosphoproteomic landscape of the DNA damage response | Poster (A) |
| 8 | Katrin | Debrich | From test tube to cell: IM30 condensates and stress response | Poster (A) |
| 9 | Jannis | Edling | Supramolecular polymer scaffolds for reversible bioconjugation using curcubit[8]uril based dynamic host-guest-chemistry | Poster (A) |
| 10 | Johanna | Geist | Ubiquitin-dependent phase separation behavior of UPS shuttle factor RAD23B | Poster (A) |
| 11 | Margarita | Gordiychuk | Searching for Sequence Features that Control DNA Cyclizability | Teaser (I) / Poster (A) |
| 12 | Christina | Goss | Non-trivial modulation of the conformation of IDRs by phosphorylation clusters | Teaser (I) / Poster (A) |
| 13 | Vladimir | Grigorev | Conformational entropy of intrinsically disordered proteins bars intruders from biomolecular condensates | Teaser (I) / Poster (A) |
| 14 | Tianshu | Gui | DVL2 condensates regulation through DDX3X and CK1ε during Wnt signaling | Teaser (I) / Poster (A) |
| 15 | Elnaz | Hosseini | Co-phase separation of TDP-43-CTD and FUS -LC: from Liquid State to Fibril State | Poster (A) |
| 16 | Anna | Hübenthal | Investigation of the condensation behavior of plant RS splicing regulators | Poster (A) |
| 17 | Amirhossein | Latifi Sasansara | Monte Carlo Simulation of Sticker-Spacer Polymers: Modeling Phase Behavior in Huntingtin Aggregation | Poster (A) |
| 18 | Donghun | Lee | Mapping Endogenous Metabolites in Biomolecular Condensates Using a Chemically Inducible Phase Separation Platform | Teaser (I) / Poster (A) |
| 19 | Susanne | Liese | Controlling Multiphase Coacervate Wetting and Self-Organization by Interfacial Proteins | Teaser (I) / Poster (A) |
| 20 | Eleanor | Liu | Understanding the role of nuclear membrane-less organelle interactions in RNA processing | Teaser (I) / Poster (A) |
| 21 | Gaëtan | Lutzweiler | Crowder-Induced Protein Condensation: Role of the Polymer Concentration and Mesh Size in Crowded Systems | Poster (A) |
| 22 | Marcos | Masukawa | Dextran-lipid droplets: endosomal escape and fate of a new class of macromolecular carrier | Poster (A) |
| 23 | Sara | Mingu | Mapping the conformational expansion of NUP62 in situ | Teaser (I) / Poster (A) |
| 24 | Alice | Mougey | Dynamics of Condensation in phase separating polymer solutions | Teaser (I) / Poster (A) |
| 25 | Maitane | Munoz-Basagoiti | Design and self-assembly of cytomotive filaments | Poster (A) |
| 26 | Clara | Neather | Agent-based modelling of phages in biofilms | Teaser (II) / Poster (B) |
| 27 | Jonas | Öftring | Toward a Field-Theoretic Description of Amyloid Aggregation Dynamics | Poster (B) |
| 28 | Oliver | Ordowski | Investigating the intrinsic modulatory effects of Ubiquitin and SUMO on the phase separation behavior of fuzzy proteins | Poster (B) |
| 29 | Diego | Paez | Proteolytic Control of an Auto-inhibitory Intrinsically Disordered Region Governs Small RNA Selectivity in Argonaute Proteins | Teaser (II) / Poster (B) |
| 30 | Devika Ghosh | Panangattu Ajaya Ghosh | Precision Engineering of Protein Oligomers to Uncover Structure-Function Relationships: Exploring Fundamental Insights and Control Cellular Functions | Teaser (II) / Poster (B) |
| 31 | Ermis | Papakonstantinou | Discovering TDP-43 Aggregation Seeds for Next-Gen Self-Assembly Peptides | Poster (B) |
| 32 | Emre | Pekbilir | TDP-43 aggregation can arise independently of phase separation | Poster (B) |
| 33 | Rajaiah | Prince Prabhu | Multivalent Polyanion Interference Restores Proteostasis in a C. elegans Tauopathy Model | Poster (B) |
| 34 | Yong | Ren | From molecular encoding to structural memory in supramolecular phase separation | Teaser (II) / Poster (B) |
| 35 | Zahra | Riazimand | Deciphering Munc13 assembly and dynamics through mass spectrometry | Poster (B) |
| 36 | Archita | Sarkar | Mapping the Structural Features of FUS: from Isolated Molecules over Oligomers to Phase-Separated Condensates | Poster (B) |
| 37 | Alina | Schaaf | Isoform-Specific Roles of BRD4 in the Regulation of Transcriptional Condensates and Gene Expression | Teaser (II) / Poster (B) |
| 38 | Tom | Scheidt | Chaperone quality control across phase boundaries | Teaser (II) / Poster (B) |
| 39 | Christian | Schmitz-Linneweber | Adapting Without Moving: Phase Separation-Mediated Control of Chloroplast RNA Metabolism under Cold Stress | Poster (B) |
| 40 | Maximilian | Schuler | Regulating Promiscuous Catalysis via Substrate-Induced Transient Assembly | Poster (B) |
| 41 | Mikhail | Suetin | Field-Theoretic Framework for Biomolecular Condensate Formation: Insights from Realistic Sequences | Teaser (II) / Poster (B) |
| 42 | Yiğitcan | Sümbelli | Intracompartmental 3D Printing of Enzymatically Active Organelle Mimics | Teaser (II) / Poster (B) |
| 43 | Damla | Tetiker | Molecular mechanism of self-repression of human condensin II and release by M18BP1 in mitosis | Teaser (II) / Poster (B) |
| 44 | Federico | Uliana | How do biophysical features govern functional activity? Dissection of the physiological relevance of TDP-43 phase separation through integrated multi-omics approaches | Poster (B) |
| 45 | Mahboob | Uvaiskaleem | Unraveling Multivalent Interactions in the Pre-Synapse | Poster (B) |
| 46 | Sára | Varga | Understanding the Role of the Aromatic Residues in Arginine-Glycine- Motifs of Disease-Linked RNA-Binding Proteins | Poster (B) |
| 47 | Madelief | Verwiel | Preservation of complex multiphase architectures in polymer-based artificial cells by photo-crosslinking | Teaser (II) / Poster (B) |
| 48 | Boyi | Wang | Condensate formation in a chiral lattice gas | Teaser (II) / Poster (B) |
| 49 | Vasileios | Xenidis | From Protonation to Sequence Grammar: All atom simulations and Protein language models to decipher liquid liquid phase separation | Poster (B) |
| 50 | Mahesh | Yadav | Biomolecular condensates with a Twist: From Assembly to Arrest | Poster (B) |
| 51 | Jiayi | Zeng | Physics of P-granule Wetting the Nucleus in C.elegans | Teaser (II) / Poster (B) |
| 52 | Tianheng | Zhu | DEAD-box RNA helicase DDX3X regulates substrate specificity of CK1ε in WNT signaling condensates | Teaser (II) / Poster (B) |
| 53 | Emanuele | Zippo | Chemically driven simulations of enzymatic phosphorylation in TDP-43 condensates | Teaser (II) / Poster (B) |
| 54 | Carolina | Silva | S100B modulates TDP−43 aggregation and phase separation | Teaser (I) / Poster (A) |
| 55 | Jasper | Michels | A minimalist view of Biopolymer Phase behaviour and aging | Poster (A) |
| 56 | Seyoon | Kim | Phase separation of amyloid-β molecules to progression of Alzheimer’s Disease | Poster (A) |
| 57 | Helle | Ulrich | Isoform-specific effects of SUMO on the phase separation of intrinsically disordered proteins | Poster (B) |
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