SFB 1551 Seminar Series Event – Prof. Dr. Andela Saric

Talk announcement for Prof. Dr. Andela Saric.

“Protein assemblies that split and merge cells across evolution”

By Prof. Dr. Andela Saric

Institute of Science and Technology Austria

Abstract from Prof. Saric:

I will present our recent research on the computational modelling of energy-consuming protein filaments that dynamically reshape and cut cells across evolution. I will first discuss the physical mechanism of ESCRT-III filaments that drive cell division and cell trafficking in archaea and eukaryotes. I will then discuss the physical mechanism behind the dynamic self-organisation of biochemically active FtsZ filaments in the early stages of bacterial division. Throughout, I will present the comparisons of our models to in vitro and in vivo data. I will finish up with our recent thoughts on the shapes of symbiotic organisms that might have led to the emergence of eukaryotes.