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SFB 1551 Seminar Series Event – Prof. Dr. Petra Beli
Methods talk by Prof. Dr. Petra Beli, Institute of Molecular Biology (IMB)
Quantitative proteomics for investigations of protein-protein interactions and phosphorylation
In this methods talk, I will provide an overview of mass spectrometry based proteomics approaches for analyzing protein-protein interactions and posttranslational modifications. I will focus on new proximity-based methods for analyzing transient and low affinity interactions that are also applicable for the analysis of phase-separated membraneless compartments. In addition, I will give an overview into the quantitative analysis of posttranslational interactions with a focus on global and targeted analysis of protein phosphorylation.